Advanced Medical and Surgical Treatments for Diabetic Retinopathy

An comprehensive guide to diabetic retinopathy treatment methods with Dr. Mahmoud Hassan, from modern injections (Eylea and Vabysmo) to retinal laser and surgery.

Latest Medical and Surgical Treatments for Diabetic Retinopathy

Diabetic retinopathy is one of the most serious chronic complications of diabetes, affecting the tiny blood vessels in the retina, which can lead to severe vision loss or even complete blindness if not treated early. With continuous scientific advancements, treatment options have evolved significantly, offering a new ray of hope for patients. In this article, we review the latest medical and surgical approaches for treating diabetic retinopathy, presented by Dr. Mahmoud Hassan, a retina and vitreous surgeon and a key contributor to Al Mashreq Eye Center in Cairo.

Modern Medical Treatments: The First Line of Defense

Medical treatments primarily focus on controlling the growth of abnormal blood vessels that appear in advanced stages of diabetic retinopathy, known as proliferative diabetic retinopathy (PDR). These vessels are fragile and prone to bleeding, leading to serious problems such as vitreous hemorrhage and retinal detachment.

1. Intravitreal Injections: A Revolution in Treatment

Injecting medications directly into the eye has brought about a paradigm shift in the treatment of diabetic retinopathy, especially in cases of diabetic macular edema (DME), which is a leading cause of vision loss in diabetic patients. These injections aim to inhibit vascular endothelial growth factor (VEGF), the protein responsible for the growth of abnormal vessels and their increased permeability.

• Anti-VEGF: This class of drugs is the most widely used and effective. Among the most prominent medications currently available are:
  • Eylea: A leading drug in this field, Eylea has demonstrated high efficacy in reducing retinal edema and improving vision in many patients. The price of an Eylea injection in Egypt for 2026 is approximately 9,000 EGP (estimated).
  • Vabysmo: This drug represents a new development, targeting both VEGF and Ang-2, potentially providing a dual mechanism of action that may be more effective in some cases, especially those not fully responsive to conventional treatments. The price of a Vabysmo injection in Egypt for 2026 is approximately 11,000 EGP (estimated).
  • Other drugs like Lucentis and Beovu.
• Corticosteroids: Used in some cases, especially when there is associated inflammation or as an alternative treatment option. Examples include the extended-release Ozurdex injection. The price of an Ozurdex implant injection in Egypt for 2026 is approximately 27,000 EGP (estimated).

It is worth noting that intravitreal injection prices are approximate and depend on the patient's individual condition and the type of medication used.

2. Retinal Laser Photocoagulation

Despite the emergence of modern injections, retinal laser continues to play a significant role, especially in the treatment of proliferative diabetic retinopathy (PDR) and in specific cases of macular edema. The goal of laser treatment is to reduce the retina's oxygen demand by treating ischemic peripheral areas, thereby decreasing VEGF secretion and preventing the growth of new abnormal blood vessels.

• Argon Laser: Typically used in advanced proliferative diabetic retinopathy to prevent bleeding and retinal contraction. The price of Argon laser (per eye) in Egypt for 2026 is approximately 5,000 EGP (estimated).
• Focal Laser: Sometimes used to treat macular edema in specific cases, where the laser is precisely directed to treat leaking points in blood vessels.

Surgical Treatments: When Other Methods Fail

Surgery is the last resort in treating diabetic retinopathy, reserved for advanced cases that have developed serious complications such as severe vitreous hemorrhage or retinal detachment.

1. Vitrectomy

Vitrectomy is the primary surgical procedure for treating the mechanical complications of diabetic retinopathy. It involves removing the vitreous humor filled with blood (in cases of vitreous hemorrhage) or the vitreous humor that is pulling on the retina causing detachment. During the operation, the surgeon can also remove fibrous membranes that form on the retinal surface, detach the retina, and repair any retinal tears.

• Simple Vitrectomy: Performed in cases of uncomplicated vitreous hemorrhage. The price of a simple vitrectomy in Egypt for 2026 starts from approximately 35,000 EGP (estimated).
• Complex / Tractional / Retinal Detachment Vitrectomy: Performed in advanced cases involving severe fibrosis on the retina or extensive retinal detachment. The average price of a complex / tractional / retinal detachment vitrectomy in Egypt for 2026 is approximately 50,000 EGP (estimated).

Some complex cases, especially those with strong traction on the retina, may require the use of auxiliary substances such as gas or silicone oil to stabilize the retina, which may require subsequent removal. The price of silicone oil removal in Egypt for 2026 is approximately 25,000 EGP (estimated). Also, cases of recurrent or complex detachment may require additional surgeries. The price for recurrent / complex detachment cases in Egypt for 2026 is approximately 50,000 EGP (estimated).

2. Other Retinal Surgeries

In some cases, additional surgical procedures may be required such as:

• Epiretinal Membrane (ERM) peeling: To remove membranes that form on the retinal surface and cause distorted vision.
• Macular Hole Surgery: While not directly related to diabetes, some diabetic patients may suffer from it. The price of macular hole surgery in Egypt for 2026 is approximately 50,000 EGP (estimated).

The Importance of Early Diagnosis and Continuous Follow-up

The key to success in treating diabetic retinopathy lies in early diagnosis and regular follow-up with a specialized ophthalmologist. Periodic fundus examination, especially for diabetic patients, helps detect any changes in their early stages before they progress and cause permanent damage. Advanced imaging techniques such as optical coherence tomography (OCT) and wide-field fluorescein angiography (FFA), available at Al Mashreq Eye Center, play a crucial role in accurately assessing the condition and determining the optimal treatment plan.

Dr. Mahmoud Hassan emphasizes the importance of adhering to the doctor's instructions, good control of blood sugar and blood pressure levels, and adopting a healthy lifestyle as essential factors for preventing the progression of diabetic retinopathy and protecting the blessing of sight.

For more information on retinal diseases and their treatment, you can follow Dr. Mahmoud Hassan's YouTube channel:.

For reservations and inquiries: 01002310813

Articles you might like to read

• Gas Injection in the Eye After Retinal Surgery: Guidelines and Recovery
• How to Preserve Your Vision After Retinal Surgery: A Patient's Guide to Home Recovery

https://drmahmoud-hassaan.com/en/articles/diabetic-retinopathy-treatment